Section 1: Using Thermal Analysis Techniques to Accelerate Preclinical Development of Pharmaceutical Products
Presenter: Genesis Infante, PhD
Do you ever wonder how pharmaceutical companies ensure the stability and efficacy of their products before they reach the market? Join us for an insightful webinar on the latest advancements in thermal analysis techniques for preclinical development of pharmaceutical products. This session will explore the critical role of thermal analysis in assessing the physical and chemical properties of active pharmaceutical ingredients and related compounds, understanding their stability, and optimizing formulation processes.
In this session, we will delve into various thermal analysis techniques, including Simultaneous Thermal Analysis (STA, TG-DTA) and Differential Scanning Calorimetry (DSC), highlighting their applications in drug discovery and pharmaceutical development. We will cover how gaining insights on the thermal behaviour of the active ingredient, such as mass loss due to degradation or dehydration, can directly impact the product development and formulation processes. In addition, the DSC method can be used to characterize crystallinity and elucidate on the effects of different states of polymorphism to the overall thermal properties.
What you will learn:
- Technique: Simultaneous Thermal Analysis, Differential Scanning Calorimetry
- Relevant lifecycle stage: Preclinical Development
- Explored applications:
- Mass loss/Dehydration of active pharmaceutical ingredients
- Sample observation capabilities – visualization of thermal events.
- Glass transitions, phase changes, melting point temperatures, and the effects of impurities.
- Processing and influence of mechanochemical treatment on thermal behavior.
- Calculating crystallinity and analyzing crystal polymorphs.
Who should attend:
- Pharmaceutical scientists and researchers involved in drug discovery.
- Researchers and formulation scientists.
- Anyone interested in learning about the applications of thermal analysis techniques in preclinical development.
This webinar will air on April 16, 2025 @ 2:00PM GMT-3.
Register here